99% 구리 펩타이드 GHK 분말

구리 펩타이드 GHK 분말은 무엇입니까?

구리 펩타이드 GHK는 글리시-l-히스토실-l-라이신으로 구성된 폴리펩타이드 (트리펩타이드-1)와 구리 이온이 결합해 형성된 복합체다.푸른색 외관 때문에 흔히 구리펩타이드 (GHK-Cu)로 불리며, 트리펩타이드-1 구리로도 알려져 있다.

1973년 미국 UCSF의 Loren Pickart 박사는 사람의 혈청으로부터 글리신, 히스티딘, 리신으로 이루어진 사람이 만든 소분자 펩타이드인 tripeptide-1 (GHK)을 분리하였는데,이 펩타이드는 간세포의 생존에 영향을 미칠 수 있는 능력 때문에 초기에 약학계에서 주목을 받았다.이상의 연구를 통해 트리펩티드-1은 금속 이온의 매우 강한 킬레이터로서 구리 이온과 안정한 청색 복합체를 형성한다는 것이 밝혀졌으며, 청색 구리 펩타이드 (GHK-Cu)이다.

구리 펩타이드 GHK는 금속 이온을 복합화할 수 있는 몇 안 되는 펩타이드 성분 중 하나로 구리 이온을 피부 손상 부위에 운반하는 운반체로 사용해 효율적인 회복 기능을 발휘할 수 있다.또한 트리펩티드-1자체가 피부 내에서 자연적으로 발생하는 신호 펩타이드로 피부 내 콜라겐 재생을 활성화시키고 안티에이징 효과를 발휘할 수 있다.

뛰어난 스킨케어 효과로 인해 구리 펩타이드 GHK는 오랫동안 여러 유명 화장품 제조업체에서 자사 제품에 사용해 왔으며, 주로 고급 제품에서 찾아볼 수 있습니다.구리 펩타이드 GHK 파우더는 안전하고 순하며 자극적이지 않아 동종의 다른 많은 주름 방지 성분보다 우수합니다.또한 GHK 파우더는 항산화, 노화방지, 항염증 등 다양한 효과가 있어 피부에 여러 가지 효과를 줄 수 있다.

그린스프링 기술은 유럽 약전, 미국 약전, 일본 약전 등의 국제 기준에 부합하는 고순도, 용제 잔류, 농약 잔류 없는 99% 구리 펩타이드 GHK 분말을 공급합니다.

2000년에 설립된 Green Spring Technology는 천연적이고 안전하며 유기농 식물 추출물을 고객에게 제공하기 위해 최선을 다하고 있습니다.우리가 제공하는 모든 제품은 EU EC396, EU 2023/915 및 최고 용매 잔류 표준을 준수하는 최고 국제 산업 표준에 맞게 제조됩니다.당사는 체계적인 품질 관리 시스템을 갖추고 ISO, HACCP 및 기타 품질 기준에 따라 엄격하게 생산을 조직합니다.우리는 Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO 및 기타 많은 인증을 통과했습니다.

규격: 

규정:

EU 규정에 부합한다.

Benefits:

Anti-Inflammatory, Antioxidant

Scientists investigated the effect of GHK-Cu powder on reactive oxygen species (ROS) and superoxide dismutase SOD activity in LPS-induced cells. The results showed a significant reduction in ROS production after pretreatment with Copper Peptide GHK at 1, 5, and 10 μM. SOD activity was significantly reduced by approximately 19% in LPS-treated cells, and increased to near control levels in cells pretreated with GHK-Cu (1, 5, and 10 μM).

To determine whether GHK-Cu reduced the release of inflammatory cytokines, the levels of TNF-α and IL-6 were confirmed by ELISA. The results showed that cells pretreated with 10 μM Copper Peptide GHK significantly reduced the secretion of these inflammatory molecules. Thus blue copper peptide reduced ROS induced by LPS and increased SOD activity while reducing the release of pro-inflammatory factors to achieve anti-inflammatory and antioxidant effects.

Promoting Hair Growth

Mouse experiments were conducted to observe the effects of the Copper Peptide GHK on hair growth in mice with the alopecia model, while liposomes of blue copper peptide (CHK-Cu) were prepared to promote transdermal absorption and maintain the advantages of maintaining a high concentration of the drug on the skin. The mice were randomly divided into 3 groups of 10 mice each, namely CHK-Cu liposome group, CHK-Cu group, and control group, and the hair growth was observed by different treatments on the hair loss area.

The results showed shorter hair growth time in the CHK-Cu liposome group and CHK-Cu group compared to the control group. light hairs grew all over the depilated area on day 6 in the CHK-Cu liposome group. On day 14, the hairs were more uniform and thicker than those in the CHK-Cu group and the control group, and the hair growth area and length were also better. Observations on the back skin of mice showed that the subcutaneous vascular network was rich and thicker in the CHK-Cu liposome group and CHK-Cu group mice, which was not obvious in the control group. Meanwhile, compared with the control group, the hair follicles in the CHK-Cu liposome group and CHK-Cu group were more fully developed and more numerous. Skin section samples were taken for hair follicle counting, and the number of hair follicles increased in both the GHK-Cu group and the GHK-Cu liposome group of mice compared with the control group, and the difference was statistically significant (P<0.05).

The experiments confirmed that nanoscale liposomes can effectively encapsulate the Copper Peptide GHK powder as well as have a better hair growth effect, which provides ideas for the development of new topical drugs for the treatment of hair loss.

Skin Tissue Repair

Copper Peptide GHK powder is a biologically active regulator naturally occurring on the alpha 2(I) chain of type I collagen in the extracellular matrix (ECM), which is released after skin damage and is an early signal for tissue repair. In addition, endothelial cells express SPARC, a stromal-type cell-secreted glycoprotein, which is degraded to produce GHK and is thought to be a source of serum GHK.

Copper ions are trace elements required for a variety of enzymatic reactions in the human body. The amount of divalent copper ions in human plasma is about 1 μg/mL, with more than 95% present in plasma cuprocyanin and the remaining 5% bound to other molecules (e.g., albumin, histidine, etc.). Due to its high affinity for copper ions, Copper Peptide GHK antagonises other molecules, competes with them for the complexation of copper ions, and acts as a carrier to deliver copper ions to the site of injury, promoting wound healing and tissue repair.

Anti-Aging & Wrinkle Removal

GHK-Cu powder can effectively enhance the functionality of fibroblasts and stimulate fibroblasts to synthesise ECM components such as glycosaminoglycans, proteoglycans, collagen, elastin, etc., to remodel the skin structure. In addition, GHK-Cu also promotes the expression of matrix metalloproteinases MMP-2, MMP-9, and their tissue inhibitors TIMPs. By regulating the activities of MMPs and TIMPs, GHK-Cu can help maintain the balance between matrix decomposition and synthesis, accelerate tissue remodeling, and improve the appearance of aging skin.

Antioxidant and Anti-Inflammatory

Studies have shown that GHK-Cu powder can inhibit inflammation by lowering the levels of acute inflammatory cytokines such as TGF-β and TNF-α. In addition, by providing copper ions to the tissues, GHK-Cu can enhance the activity of superoxide dismutase, thereby inhibiting the generation of reactive oxygen radicals and achieving antioxidant efficacy.

Applications:

In Cosmetics:

Copper Peptide GHK acts on the dermis to promote the synthesis of extracellular matrix, such as collagen and glycosaminoglycans, resulting in thicker, firmer skin. It also stimulates fibroblast synthesis, promotes collagen and elastin neogenesis, increases blood vessel growth and anti-oxidant power, and repairs damage quickly. In high-end skincare products, Complex Copper Peptide GHK Powder can repair DNA damage, dismantle abnormal collagen fibres that form scars and wrinkles, and rebuild normal pattern proteins, with excellent repair and anti-aging effects.