Berberine 하이드로 클로라이드 분말

베르베린 하이드로 클로라이드 분말은 무엇입니까?

염산베르베린은 황련, 느티나무껍질, 산구나무 등 식물의 리좀에서 추출한 다양한 활성을 가진 이소퀴놀린 알칼로이드이다.열을 맑게하고 해독, 설사를 멎게 하는 기능이 있어 한의학에서 널리 쓰인다.그것의 초기 임상 적용은 주로 항균 목적이었다.

 위장관의 염증 치료에 활성 성분으로서 염화버베린은 과민성 대장 증후군으로 인한 이질 및 설사의 치료에도 좋은 효능을 보였다.그것은 이질을 퇴치하기 위해 처방전 없이 널리 사용되어 왔다.또한 혈당과 지질대사 조절, 동맥경화증 예방, 항부정맥, 종양세포 증식 억제 및 항바이러스 등에 상당한 효과가 있다.

녹색 봄 기술은 98% 베르베린 염산염 분말 또는 과립을 공급합니다.우리는 Coptis Chinensis 또는 Phellodendron chinense Schneid 로부터 염화버베린을 공급합니다.자연 API입니다.

그린스프링테크놀로지 (Green Spring Technology)는 2000년에 설립된 중국의 대표적인 생명공학 기업으로 천연, 안전, 유기농 식물 추출물을 고객에게 제공하는 데 주력하고 있다.Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO9001, ISO22000 등과 같은 많은 인증을 획득했습니다.그린스프링은 체계적인 내부 품질관리 시스템을 갖추고 ISO, HACCP 등 품질기준에 따라 생산을 체계화하고 있다.이 제품은 EU EC396, EU 2023/915 및 최고 용매 잔류 기준을 준수합니다. 

규격:  

규제:

EU 규정에 부합한다.

Benefits:

Bacterial Inhibition

The Chinese medicine Berberine Hydrochloride has the effect of clearing heat and removing toxins, and it has been used for thousands of years to treat diarrhoea. Berberine Hydrochloride (Berberine Complex) can fully exert its inhibitory effect on intestinal bacteria such as Shigella dysenteriae, Shigella fumigatus, Salmonella, and Staphylococcus aureus, and at the same time, it maintains the intestinal microenvironmental homeostasis as well as protects the mucous membranes of the gastrointestinal tract, thus resolving diarrhoea caused by intestinal infections.

Hypoglycaemic

Under the stimulation of glucose, berberine hydrochloride can increase insulin secretion and cell proliferation in MIN6 islet cells, which can act as an insulinotropic agent; berberine hydrochloride can also activate the adenosine phosphate-activated protein kinase signalling pathway to restore damaged islet cells and promote insulin secretion in rats.

Berberine hydrochloride can effectively inhibit the production of pro-inflammatory cytokines such as interleukin-6 and tumor necrosis factor-alpha, modulate the expression of insulin receptor substrate 1 and serine/threonine kinase phosphorylation, thus improving the insulin signalling cascade and insulin resistance. It has the application prospect of assisting in the control of blood glucose.

Anti-Inflammatory

Berberine hydrochloride has significant anti-inflammatory effects, mainly through inhibiting the production and activity of inflammatory factors. In a variety of inflammatory diseases, berberine hydrochloride tablets can exert excellent anti-inflammatory effects, such as gastroenteritis, pneumonia and so on. Berberine hydrochloride can effectively inhibit the adhesion of leukocytes, the activation of NF-κB, and the production and release of inflammatory factors such as TNF-α, IL-1β, IL-6, TGF-β, and IL-8.

Beneficial to Cardiovascular Health

Berberine hydrochloride has been widely studied in cardiovascular diseases, as K+ channels, Ca+ channels, cholinesterase, M receptors, adenosine receptors, etc. can be targeted by berberine hydrochloride, therefore, berberine hydrochloride is also a valuable lead compound for cardiovascular diseases and has a promising application.

Antihypertensive

The mechanism of action of safranin in antihypertension is mainly to competitively block the α-receptor of vascular smooth muscle, to reduce peripheral vascular resistance; in addition, it can also enhance the action of acetylcholine through the activity of anticholinesterase, to make the vasodilatation.

Reduces Blood Glucose

Berberine hydrochloride inhibits mitochondrial glucose oxidation and stimulates glycolysis, subsequently increasing glucose metabolism; it reduces ATP levels by inhibiting mitochondrial function in the liver. It inhibits the activity of DPP 4 (a ubiquitous serine protease), which cleaves certain peptides, and they act to increase insulin levels in the presence of high blood sugar. Berberine hydrochloride has beneficial effects on improving insulin resistance and glucose utilization in tissues by lowering lipid (especially triglyceride) and plasma free fatty acid levels.

Antioxidant

The metabolites of berberine hydrochloride and berberine have been shown to display excellent -OH scavenging activity, which is roughly comparable to that of vitamin C, a potent antioxidant. An increase in SOD (superoxide dismutase) activity and a decrease in MDA (a marker of lipid peroxidation) levels were monitored when berberine was administered to rats modeled with diabetes. Further results showed that the scavenging activity of berberine is closely related to its ferrous ion chelating activity, and the C-9 hydroxyl group of berberine is an essential part.

Applications:

In Pharmaceutical:

Berberine Hydrochloride Powder as a natural ingredient, it has been made into pressed tablets, capsules, and many other dosage forms for the treatment of intestinal infections, diarrhea and other conditions.