Alpha Lipoic 산 대량 분말

알파 Lipoic 산성은 무엇 입니까?

리포산은 1950년에 미국의 학자 리드 등이 돼지간에서 분리해냈으며 오늘날에는 합성방법으로 얻을수 있다.리포산은 필수적인 영양소이다.인체도 지방산과 시스테인으로부터 일부 자체의 리포산을 합성할수 있지만 이것만으로는 수요를 만족시키기에는 턱없이 부족하며 신체 's 리포산 합성 능력은 나이가 들수록 감소하므로 음식을 통해 보충할 필요가 있다.식물에서 지방산 함량이 가장 높은 것은 시금치이고 그 다음이 브로콜리, 토마토이며 동물에서 가장 함량이 높은 것은 동물의 신장과 간에서 발견된다.

알파 리포산은 강력한 항산화 성질을 가지고 있는 것으로 밝혀졌으며 지용성과 수용성 환경 모두에서 항산화 능력을 발휘하는 것으로 알려진 유일한 물질이다.리포산은 반응성 산소 라디칼의 직접적인 청소, 유리 금속 이온과의 킬레이트, 내인성 항산화제의 재생 촉진 등을 통해 체내에서 강력한 항산화 스트레스 역할을 할 수 있으며, 산화 스트레스는 당뇨병, 심혈관 질환, 간 질환, 종양 등과 같은 다양한 질병의 병리적 근거가 되어 알파 리포산이 다양한 임상 전신 질환에서 예방 및 치료 역할을 할 수 있습니다.

그린 스프링 기술은 식품 등급 알파 리포산 대량 분말을 공급하며, 농약 잔류량이 적고, 용제 잔류량이 없습니다.유럽 약전, 미국 약전, 일본 약전 등 국제 표준을 엄격히 준수한다.권위 있는 타사 테스트 보고서를 사용할 수 있습니다.

규격:

규정:

EU 규정에 부합한다.

Benefits:

Neuroprotective Effects

Free radical-induced injury is an important component of secondary neuronal brain damage in stroke treatment, and there is no effective treatment to prevent this effect. Alpha Lipoic Acid’s antioxidant properties have been linked to its neurorestorative and neuroprotective effects. Alpha lipoic acid administered via the jugular vein reduces mortality, neurological deficit scores, and infarctions, and increases neurogenesis and cerebral cellular metabolism, resulting in a neuroprotective effect. effects. α-Lipoic acid induces microglia M2 phenotype, regulates the expression of pro-inflammatory cytokines IL-6, IL-1, IL-10, and tumor necrosis factor (TNF), and inhibits transcription factor NF-κB, a key mediator of an inflammatory response (Wang et al., 2018).

Beneficial for Neurodegeneration

In Parkinson's disease, MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a neurotoxin that causes loss of dopaminergic cells in a mouse model (Langston 1985). This novel toxin triggers the death signaling pathway through activation of mouse substantia nigra compacta (SNpc) apoptosis signal-regulated kinase 1 (ASK1) and translocated death structural domain-associated protein (DAXX); alpha lipoic acid terminates this cascade of responses and provides neuroprotection (Karuna-karan et al. 2007). Oxidative stress is responsible for the degeneration of dopaminergic neurons in Parkinson's disease patients, and α-lipoic acid mediates the inhibition of the p53 protein, which increases the expression level of nuclear antigens in proliferating cells (Li et al. 2016).

Several studies have found that alpha-lipoic acid in combination with omega-3 fatty acids has a synergistic effect on slowing functional and cognitive decline in Alzheimer's disease (Shinto et al. 2014). In scopolamine-induced memory loss, alpha lipoic acid inhibits brain weight loss, down-regulates oxidative tissue damage leading to neuronal cell loss, repairs memory, and motor function, reduces proliferation of reactive astrocytes, and reduces chromatin lysis in cerebellar-hippocampal cortex (Bastianetto and Quirion 2004).

Beneficial for Cardiovascular Disease

Dihydrolipoic acid has been reported to have properties that regulate blood lipids, prevent oxidation of low-density lipoproteins, and regulate hypertension, suggesting that alpha lipoic acid may be a possible protective agent against cardiovascular disease (Wollin and Jones 2003). As alpha-lipoic acid intake increased, the incidence of cardiovascular disease decreased.

Beneficial for Kidney-Related Diseases

Alpha-lipoic acid taken with antioxidants such as alpha-tocopherol or vitamin E and N-acetylcysteine can help dialysis patients with elevated oxidative stress (Lim et al. 1999; Nazrul et al. 2000; Roob et al. 2000; Leehey et al. 2005). alpha-lipoic acid has better antioxidant activity than N-acetylcysteine against oxidative stress, including diabetic neuropathy and glomerular damage. glomerular injury.

The antioxidant activity of alpha lipoic acid is superior to that of N-acetylcysteine.α-Lipoic acid leads to a decrease in markers of oxidative stress (LDL oxidative and plasma protein carbonyls); therefore, it is noteworthy that administration of this drug reduces oxidative stress induced by intravenous iron (Marangon et al., 1999). However, in diabetic nephropathy, TGF- β1 is associated with MAPK and induces the production of connexin in tethered cells. Alpha lipoic acid ameliorates proteinuria by reducing the expression of TGFβ1 and connexin (Lee et al., 2009). Patients with autosomal dominant polycystic kidney disease treated with α-lipoic acid showed significant improvements in metabolism, inflammation, and endothelial function (Lai et al. 2020).

Beneficial for Inflammatory Lesions

Alpha lipoic acid is a short-chain fatty acid that is synthesized in the body and acts as an antioxidant, protecting the body's cells from damage and helping to restore the scale of other antioxidants such as vitamins C and E (Moura et al. 2021). Several studies have shown that α-lipoic acid in combination with fructose can reduce fructose-induced inflammation, hepatic oxidative stress, and insulin resistance.

Studies have also found that alpha-lipoic acid can act as a chemopreventive agent as it inhibits inflammation associated with carcinogenesis (Moon 2016). Alpha-lipoic acid powder reduces markers of inflammation in patients with heart disease as oxidative stress is thought to be a major cause of many cardiovascular diseases, including hypertension and heart failure. Oxidative stress is increased during the aging process, leading to enhanced ROS production or reduced antioxidant safeguards. The incidence of heart disease is directly related to a person's age.

Applications:

For Health Product:

As a dietary supplement, alpha lipoic acid powder has become a common ingredient in conventional products such as anti-aging supplements and multivitamin preparations. alpha-lipoic acid is increasingly used in dietary supplements due to its antioxidant and anti-diabetic properties. At the same time, it improves aging-related cognition, diabetes, cardiovascular and erectile dysfunction, neuromuscular loss, and cancer.