사과 껍질 추출물 98% Phloretin

사과 껍질 추출물 플로레틴은 무엇입니까?

Phloretin은 dihydrochalcone 구조를 가진 식물성 폴리페놀로, 사과나무의 뿌리 껍질에 집중되어 있다고 해서 붙여진 이름이다.플로레틴은 주로 사과 가지와 잎, 사과 과일/껍질, 사과 나무 리좀/껍질, 리치 과일 껍질, 그리고 다른 많은 식물들에서 발견된다.

Rhizophorin은 단일화합물이고, Rhizophorin은 glucoside이다.그것은 트리 히드 록시 페놀 아세톤, 2.4.6-트리 히드 록시-3-(4-히드 록시 페닐) 프로 피오 페논의 화학 이름과 함께 플라보노이드의 디 히드로 칼 콘 그룹에 속하며, 약간 노란색 바늘과 같은 결정입니다.수용성은 함량이 적으면 아주 좋고 함량이 많으면 잘 용해되지 않으며 에탄올에 쉽게 용해된다.

그린 스프링 기술은 고순도, 안정적인 기능, 용제 잔류, 중금속, 농약 잔류, 그리고 미생물은 유럽 약전, 일본 약전, 미국 약전 및 기타 국제 기준에 따라 사과 껍질 추출물 98% Phloretin을 공급합니다.

녹색 스프링테크놀로지는 2000년 설립돼 고품질의 식물 추출물 개발 및 공급에 주력하고 있는 중국 대표 생명공학 기업이다.당사의 제품은 EU EC396, EU 2023/915 및 최고 용매 잔류 표준을 준수하는 최고 국제 산업 표준에 맞게 제조됩니다.우리의 제품은 할랄, 코셔, 코스모스, BRC, IFS, FDA, ISO 등에 의해 인증되었습니다.권위 있는 타사 테스트 보고서를 사용할 수 있습니다. 

규격: 

규제:

EU 규정에 부합한다.

Benefits:

Antioxidant

Phloretin has strong antioxidant properties and scavenges free radicals in the skin. Rhizopusin, the glucoside of rhizopus, has also been shown to have antioxidant activity, with 3-hydroxyrhizopus being able to scavenge peroxides, free radicals, and lipid peroxidation. Rhizopusin inhibits the release of nitric oxide from stimulated macrophages and reduces macrophage phagocytosis, with potential anti-inflammatory effects.

Anti-Inflammatory

Phloretin and epicatechin are the strongest inhibitors of cyclooxygenase 1, and rhizopus is a known competitive inhibitor of D-glucose co-transporter proteins, giving rhizopus a potential anti-inflammatory effect.

Sun Protection

Phloretin has a certain UV-absorbing capacity. Phloretin absorbs UV rays directly but also enhances the expression of nucleotide excision repair genes. It slows down UVB-induced pyrimidine dimer formation, glutathione degradation, and cell death, reducing UV damage to keratinocytes.

UV irradiation can cause cells to produce reactive oxygen species and free radicals, both of which are extremely unstable and prone to a series of oxidative chain reactions that ultimately damage cells. Adding rhizomes to cosmetic base formulations can increase the SPF and SPA values of cosmetics. In addition, a mixture of rhizomes, VC, and ferulic acid can protect human skin from UV rays and provide photoprotection for human skin.

Whitening and Anti-Aging

Phloretin inhibits melanocyte activity and has potential whitening effects. It has been found that 3-hydroxyrhizoderma shows potent antioxidant and tyrosinase-reducing effects in human epidermal melanocytes. The powerful antioxidant activity gives rhizopodophyllin an anti-aging effect. Phloretin analogs also have inhibitory activity on xanthine oxidase and elastase, which can inhibit the synthesis of MMP-1 in human fibroblasts and reduce the decomposition of collagen and other components, thus inhibiting skin aging.

Bacteriostatic

Phloretin is a flavonoid compound with antibacterial activity. It has been found that phloretin has a strong inhibitory effect on Gram-positive bacteria, especially on Staphylococcus aureus, Listeria monocytogenes and Salmonella typhimurium. In addition to its bacteriostatic activity against pathogenic bacteria, rhizopin is also useful against common skin bacteria.

The MIC of phloretin on both Propionibacterium acnes and Propionibacterium granulosum was 0.5mg/L. Meanwhile, the results of the clinical trial showed that there was a significant reduction of whiteheads, blackheads, pimples, and sebum secretion in the subjects after usingphloretin for 4 weeks. The inhibitory effect of phloretin on bacteria is on the one hand to act on the bacterial internal enzyme protein system, affecting the bacterial energy metabolism and bacterial growth of oxidative damage repair; on the other hand, it interferes with the synthesis of intracellular proteins, so that the metabolism of the cell is disturbed, which ultimately leads to the death of the bacteria.

Transdermal Permeation

Phloretin has a very safe and effective transdermal permeability effect, which enhances the transdermal permeability of drugs. Multiple studies have confirmed that Phloretin and 6-ketocholanol interact with the lipid layer and alter the structure of the cell membrane, resulting in greater fluidity. As a transdermal permeation enhancer, rhizopin can facilitate the absorption and utilization of other potent ingredients in the formulation, making them more effective.

Applications:

In Cosmetics:

Apple Peel Extract Phloretin is a flavonoid compound with a dihydrochalcone structure, which can inhibit the excessive secretion of sebaceous glands and is used for the treatment of exuberant secretion acne; it can inhibit the activity of melanin cells and is useful for various skin discolorations. It has a variety of effects such as antioxidant, anti-inflammatory, whitening, sunscreen, antibacterial, moisturizing, etc., and has been widely used in many types of cosmetics and care products such as creams, lotions, essences, gels, and conditioners.

In the Food Field:

Apple Peel Extract Root Phloretin is also a very unique natural bitter taste inhibitor and flavor modifier, which can inhibit bitterness and other unpleasant tastes in food and improve the taste. It reduces off-flavors present in high-intensity sweeteners and masks their undesirable flavors. It can be widely used in beverages, tablets, soft candy, and other varieties.