Diosgenin 파우더

디오게닌 (Diosgenin) 이란?

일반적으로 디오스게닌으로 알려진 디오스게닌은 식물에서 자연적으로 합성된 스테로이드 디오스게닌의 일종으로 콩과 디오스코리아과 식물의 덩이줄기에 널리 존재한다.그것은 스테로이드 호르몬 약물의 합성을위한 중요한 원료입니다.항암, 항염증, 항산화 등 많은 놀라운 약리학적 효과가 있으며 높은 약효를 가지고 있다.

그린 스프링은 야생 참덩이줄기에서 추출한 디오스게닌 파우더를 제공합니다.천연 DHEA (dehydroepiandrosterone) 성분으로 피부 표피세포의 신진대사를 촉진하고 피부의 보습 기능을 강화하며 체격 개선에도 도움을 준다.

규격: 

규제:

EU 규정에 부합한다.

Benefits:

Antitumor Activity

In vivo and in vitro studies have shown that diosgenin has cytotoxicity to a variety of tumor cells, including breast cancer cells, colon cancer cells, prostate cancer cells, lung cancer cells, gastric cancer cells, Osteosarcoma cells, etc. It can play an anti-tumor role by inhibiting tumor cell proliferation, inducing tumor cell apoptosis, blocking cell cycle, and anti-tumor metastasis.

Hepatoprotective Effect

Diosgenin powder can effectively inhibit the cell viability of HSC-T6, LX-2, and primary rat hepatic stellate cells (HSCs), while liver cells are not affected. Diosgenin also has a good protective effect on alcoholic liver injury, which is achieved by reducing oxidative stress, the production of inflammatory cytokines, cell apoptosis, and liver steatosis.

Hypoglycemic Effect

The combination of NPH insulin and diosgenin in the treatment of elderly type 2 diabetes is more effective in reducing blood sugar with good safety, which may be related to the reduction of Glycated hemoglobin formation.

Anti Osteoporosis Effect

Dioscin can promote the proliferation of osteoblasts and inhibit the formation of Osteoclast. Research has shown that after diosgenin treatment of MC3T3-E1 cells, ER- α、 ER- β、 Lrp5 β- The expression of both catenin and Bcl-2 proteins increased, and the ratio of OPG/RANKL increased, depending on the LRP5 pathway, thereby promoting osteoblast proliferation.

Applications:

Pharmaceutical Intermediate:

Diosgenin powder is an important steroidal saponin and an important raw material for Semisynthesis steroidal compounds.