Naringin 파우더

Naringin 이란 파우더?

Naringin, Naringin 로도 알 려 진, Citrin 및 Isohesperidin, 자몽은에서 고립 dihydroflavonoid 껍질을 벗기고 쓴 맛을 가지고 있다.그것의 껍질과 펄프에서 자연적으로 발생 한 자몽, 귤, 그리고 오렌지 Brassicaceae 가족에 있다.Naringin은 하나의 주요 Boneset 같은 전통적인 중국에서 적극적인 재료 약품, 감귤 aurantium 감귤 aurantium 감귤류 aurantium, 그리고 감귤류 aurantium.다양한 식물의 나린진 함량은 종과 원산지에 따라 크게 달라지는데, 보통, 미성숙한 열매에서 나린진의 함량이 더 높다.현대 약리학적 연구에 따르면 나린진은 항 골다공증, 항산화, 항 염증, 항균, 심근 및 간 손상 개선, 당뇨병 및 합병증의 예방 및 치료.

봄에 의해 제공 되는 자연 naringin 파우더 녹색 기술은 Rutaceae 식물의 열매에서 추출 한 감귤류 그 랜 디 (l)Osbeck다.이 naringin 파우더 제품은 원시 재료들을 완제품에서 추적 할 수 있는 제어 할 수 있고, 엄격 한 원자재 잔류 농약의 감시하고 있다.다양 한 오염물질의 탐지 글로벌 기준을만 난다.naringin 파우더의 우리는 다양 한 컨 텐 츠를 제공 할 수 있, 98%에게 달 려 있다.품질이 안정 되고은 여러 품질 인증을 통과하였다.

규격: 

규제:

EU 규정에 부합한다.

Benefits:

Preventing Osteoporosis

Studies have shown that naringenin has significant advantages in the treatment of osteoporotic bone damage and has the effect of preventing osteoporosis, promoting fracture healing, and repairing cartilage damage. Naringin can increase the expression of osteoblast marker proteins [such as osteocalcin, osteoblastin, osteoprotegerin, and bone formation protein-2 (BMP-2)], and also inhibit RANKL [The receptor activator of nuclear factor-kappa B (NF-κB) ligand (RANKL)]-induced NF-κB and ERK signaling. κB and ERK signaling activity and protein expression of osteoclast genes, which leads to the inability of osteoclasts to form normally, and therefore, serves to delay osteoporosis and promote the proliferation and differentiation of osteoblasts.

Antioxidant

Naringin has significant antioxidant and ameliorative effects on oxidative damage and has some pharmacological value to be developed as a natural antioxidant. The main mechanism of antioxidants is related to the scavenging of free radicals such as DPPH, AAPH, and ABTS by naringin, antagonizing their attack on cells, inhibiting the generation of ROS, and blocking the oxidative reaction of the body; regulating the content of various oxidative enzymes in the body, such as SOD, GSH, GST, MDA, MPO and so on, and repairing the damage caused by the oxidative stress of the body.

Naringin has a hydroxyl group in its molecular structure, which can react with harmful free radicals to become more stable semiquinone radicals to play an antioxidant role. By comparing the scavenging ability of naringin and ascorbic acid on 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, it was found that naringin has a better scavenging effect on DPPH free radicals.

Antibacterial and Anti-Inflammatory

Studies have shown that naringin has a good anti-inflammatory effect, can improve the endotoxin lipopolysaccharide (LPS)-induced inflammatory injury, has the ability to inhibit the protein and gene expression levels of interleukin-6 (interleukin-6, IL-6), IL-8, IL-1β in the inflammation model, and reduces the concentration of leukotriene B4 (leukotriene B4, LTB4) and tumor necrosis factor-α (TNF-α). leukotriene B4 (LTB4) and tumor necrosis factor-α (TNF-α) concentrations. Meanwhile, it was also found that the inhibitory effect of naringin combined with filaggrin on inflammatory factors was significantly stronger than that of naringin or filaggrin alone, indicating that the combination of naringin is of great significance in improving the clinical efficacy, improving the body's tolerance to the drug, and exerting the best anti-inflammatory efficacy.

Improvement of Myocardial and Hepatic Injury

Naringin has an ameliorative effect on common in vivo and in vitro experimental myocardial injuries. The mechanism is related to the fact that naringin regulates the expression of apoptotic factors, inhibits myocardial tissue protein phosphorylation, and blocks the activation of the inflammatory pathway NF-κB after myocardial ischemia/reperfusion injury (MI/RI) and hypoxia/reoxygenation injury (H/R).

Naringin is effective in the study of preventing and treating experimental liver injury, and has certain pharmacological effects. The mechanism is related to the fact that naringin can significantly reduce CYP450 activity, inhibit I-phase enzyme metabolism, promote II-phase enzyme metabolism, and eliminate the damage of exogenous substances on hepatocytes; it is also related to the regulation of a variety of intracellular oxidative enzymes, inhibition of oxidative damage, apoptosis of hepatocytes, and further repair of damaged hepatocytes.

Applications:

In the Food Field:

Naringenin powder can be used as naringenin both a natural color, flavor modifier and bittering agent in the production of food and beverages. It can also be used as a raw material for the synthesis of sweetness, non-toxic, low-energy new sweetener dihydronaringenin chalcone and neohesperidin chalcone.

In Cosmetics:

The main role of naringin in cosmetics and skin care products is as a skin conditioning agent.

In Pharmaceutical:

Naringin has anti-inflammatory, anti-viral, anti-cancer, anti-mutagenic, anti-allergic, anti-ulcer, analgesic, blood pressure lowering activity, can lower blood cholesterol, reduce the formation of thrombus, improve the local microcirculation and nutrient supply. The Naringin powder can be used in the production of the prevention and treatment of cardiovascular and cerebrovascular diseases.