Sophora Japonica 추출물 Kaempferol

Sophora Japonica 추출물 Kaempferol은 무엇입니까?

Sophora Japonica extract kaempferol은 Sophora Japonica의 열매에서 추출한 활성 성분 kaempferol입니다.그것은 노란색 결정 성 분말이며 물에 약간 용해되며 뜨거운 에탄올, 에테르 DMSO 및 기타 유기 용매에 용해됩니다.켐페롤은 강한 항산화 성질을 가지고 있어 체내에서 과다한 과산화라디칼을 걷어내고 DNA와 세포의 산화적 손상을 막을 수 있다.그것은 주로 항암, 출산 억제제, 항 간질, 항 염증, 항산화, 항 궤양으로 사용됩니다.

녹색 스프링테크놀로지는 순도가 최대 98%에 달하는 고순도 Sophora Japonica 추출물 Kaempferol을 공급하며, 나노입자, 리포소말 나노입자 및 기타 형태로 사용 가능합니다.나노입자 켐페롤은 물에 녹기 어려운 문제를 해결하고,보다 강한 용해도, 안정성, 유화, 항산화 특성을 가지고 있어 의약품 원료로 사용되고 있다.

2000년 설립, 그린 봄 기술은 고품질의 식물 추출물의 연구 및 개발에 전념하는 중국의 선도적인 생명 공학 회사입니다.Halal, Kosher, COSMOS, BRC, IFS, FDA, ISO9001, ISO22000 등과 같은 많은 인증을 획득했습니다.체계적인 내부 품질 관리 시스템을 갖추고 ISO, HACCP 및 기타 품질 기준에 따라 엄격하게 생산을 조직합니다.이 제품은 EU EC396, EU 2023/915 및 최고 용매 잔류 기준을 준수합니다.

규격: 

규제:

EU 규정에 부합한다.

Benefits:

Antibacterial and Anti-Inflammatory

Studies have shown that kaempferol has good antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA). The K-Br paper slide method shows that a concentration of 50 mg/tablet can make the circle of inhibition of MRSA up to 8.5 mm, and its antibacterial activity against Vibrio cholerae and Enterococcus faecalis is also very good. In antiviral, kaempferol showed concentration-dependent inhibition at non-cytotoxic concentrations. In anti-inflammation, kaempferol mainly inhibits the expression of inflammatory factors to achieve anti-inflammatory effects.

Contributes to Anticancer

Kaempferol was applied to human gastric cancer cells MGC-803 (in vitro assay), and DAPI staining was observed under a fluorescence microscope, and the results showed that the chromatin of the nucleus was condensed, and the nucleus was dissolved and irregularly shaped. According to the results of the MIT method, it was found that kaempferol could inhibit the proliferation of cancer cells. According to the comet electrophoresis method, most of the cancer cells showed a comet tail shape, which resulted in cellular DNA damage, and finally concluded that kaempferol could inhibit the proliferation of human gastric cancer cells.

Beneficial for Diabetes

Researchers established a mouse model to verify the hypoglycemic and hypolipidemic effects of kaempferol in diabetic mice. Serum triglyceride, total cholesterol, blood glucose, malondialdehyde, glutathione peroxidase, and superoxide dismutase activities were measured in diabetic mice fed with kaempferol and diabetic mice fed with thirst-quenching pills in a control test.

The results showed that kaempferol could effectively reduce serum triglyceride, total cholesterol, blood glucose, and malondialdehyde levels in mice, and significantly increase the activities of serum glutathione peroxidase and superoxide dismutase, with 10 mg/(kg-bw-d) as the optimal dose. Kaempferol can delay the development of diabetes mellitus. The above studies have demonstrated the therapeutic effect of kaempferol on diabetes mellitus.

May Beneficial for Hepatoprotection

In a mouse model of acute liver failure with kaempferol, kaempferol improved hepatic function and pathological changes in mice and inhibited endoplasmic reticulum stress-induced apoptosis in human hepatocyte cell line 7702 cells. It may protect hepatocytes by inhibiting endoplasmic reticulum stress through inhibiting the expression of the endoplasmic reticulum stress-specific apoptotic protein CHOP, which suggests that the use of kaempferol may provide a new intervention for acute liver injury.

Applications:

In Pharmaceutical:

Sophora extract kaempferol is a widely used natural compound with various biological activities such as antioxidant and anti-inflammatory. Due to its unique physicochemical properties, Kaempferol is widely used in various fields. In the field of medicine, kaempferol is mainly used in the treatment of cardiovascular and neurological diseases. In addition, it is used in the preparation of some anticancer drugs and antiparasitic drugs.